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Rev. Hugh Alison, born in PA about 1740, graduated from Princeton,1762. Ordained Presbyterian minister by 1766. Moved to SC, 1766, pastored church in James Island(Charleston). He married Dorothea Smiser, Jan. 11, 1770 and they had three children: Jacob Hyleman, Regina, and Martha.
William began his public duties of the ministry, as an ordained Presbyterian minister. He was pastor of the Presbyterian Churches at Dorchester and Beech Hill from 1815-1821, when he received a call to the Presbyterian Church of Edisto Island. The Presbyterian Church on Edisto, was organized between 1690 and 1700, and is one of the oldest church edifices in the state. By 1871, the congregation had grown from 25 members to 662, and he had married 78 couples. He had preached there, except for a short period during the War between the States, until his death, in 1875 a term of fifty-two years.
In 1816, he married Mary Canty Villeponteaux, the youngest daughter of Peter Villeponteaux and his wife Sarah, (nee Lockwood). Peter was a grandson of Zachariah Villeponteaux, a member of the first and earliest Huguenot families who emigrated from France after the revocation of the Edict of Nantes. He is said to have landed in New York, and remained there for a short while practicing law, before removing to South Carolina, where he settled somewhere in the vicinity of Goose Creek.